We strongly recommend that you refer to our 4-Step Bed Bug Treatment Guide before using Crossfire Bed Bug Concentrate for detailed information on how to prepare a room for a bed bug treatment, how to treat a room for bed bugs, how to treat a mattress for bed bugs, how to kill live and active bed bugs and the importance of repeat bed bug treatments. Pets should be removed from the area you are treating, and can return to the area once the application has completely dried.