Yes, OHP Fireworxx Herbicide is a non-selective herbicide that can be used for ornamentals, but we recommend checking with the manufacturer if it has been tested on or found effective on that species. However, we would suggest a Glyphosate product as it tends to be effective and efficient when treating lesser celandine. In addition, using a surfactant with the herbicide will increase the effectiveness, as the leaves may be waxy, so it will help stick to the lesser celandine better. Feel free to find additional information on lesser celandine here.