Steve from Maryland writes
Virginia buttonweed is hard to treat. Although Killzall Weed and Grass Killer is not specifically labeled to treat it, it does contain glyphosate, and most products containing this ingredient will kill whatever they are applied to. We have found that EndRun works great on Virginia buttonweed when applied per label. Blindside also is labeled to suppress Virginia buttonweed.
Answer last updated on: 10/21/2019