There should be no issue using Bayer Advanced All-In-One Rose and Flower Care Granules around brunnera. Rates would fall under flower bed application on the label.
Bio Advanced All-In-One Rose and Flower Care - Granules should not be applied to any potted, containerized plants or in flower boxes. It is safe for applications in the soil as directed to Roses, Flowers, Iris, Hibiscus, Azaleas, Camellias, Rhododendrons and other shrubs.
Bio Advanced All-In-One Rose and Flower Care - Granules can be applied to roses, flowers, hibiscus, azaleas, rhododendrons, camellias and other shrubs.
Bio Advanced All-In-One Rose and Flower Care - Granules can be applied during high heat temperatures outdoors however you want to be sure that you do not apply the granules directly to leaves or other green parts of the plants. We recommend applying in the morning or evening when temperatures are at the coolest for the day rather than during the middle of the day when it’s the hottest.
Follow the application directions per the product label.
Bio Advanced All-In-One Rose and Flower Care-Granules states on the product label:
For Established Plants:
Apply when plants have about one inch of new growth in the spring and reapply every six weeks through the end of summer. Follow directions for Flowers and Ornamental Shrubs.
For Ornamental Shrubs (Camellias):
Apply 2/3 cup, 6 oz. for each foot of shrub height (2 cups for 3’ high shrub). Distribute the required amount evenly from the base to the dripline of all sides of the plants. Work into top 1 to 2 inches of soil and water in thoroughly.
Bio Advanced All-In-One Rose and Flower Care - Granules can be applied to roses, flowers, hibiscus, azaleas, rhododendrons, camellias and other shrubs. You will use 1/2 capful per foot of plant height. Please refer to the product label for a complete list as well as application instructions.