Premise 2 Termiticide will not move through the soil as it binds to the soil where it is applied. The only way that it would affect termite colonies below ground is if the workers from those colonies are coming and going through treated soil when you apply as a trench around the home.
Premise 2 Termiticide would be applied to the soil before the home is set on the ground if directly placed there. After building, it would be applied in a trench around the skirting. We have a step by step guide that will walk you through how to do your own termite trenching treatment. You can see the guide by clicking on the link here.
Premise 2 Termiticide can be used in drilled holes if they are ones that were previously drilled for termite applications only. It cannot however just be sprayed inside walls as any part of prevention.