It is best to allow the DF 5000 Drain Gel to be allowed to work for at least 7-8 hours, so it would not be recommended to use a treated drain until that amount of time has passed. What we usually recommend is that you treat the drains right before going to bed, so that the product can work overnight.
Since insecticides would not be labeled to be applied to or poured into drains and DF 5000 Drain Gel should only be used in drains to remove the organic buildup that develops and provides a breading ground for insects, there should not be any issue an insecticide removing or compromising the application of drain gel.