ZoGuard Plus For Cats


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{ $27.99 { $27.49
  Size/Description Price/Ea. Qty
ZoGuard Plus For Cats box (3 doses)

Buy 1: $27.99 each

Buy 2 or more: $27.49 each

Total Price: $0.00

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ZoGuard Plus For Cats
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ZoGuard Plus for Cats is the perfect solution to help protect your cats against fleas and ticks. It uses Fipronil and S-Methoprene (insect growth regulator) as its active ingredients (same as leading competitor, FRONTLINE Plus) which effectively kills fleas, ticks (including those that may transmit Lyme disease) and chewing lice. It also prevents flea eggs and flea larvae from maturing by breaking its cycle. ZoGuard features a sustained release formula which was developed to offer quick and long-lasting control, but with better value for the money. Product comes with three 0.50 ml (0.017 fl oz) applicators and is ideal for cats and kittens over 8 weeks of age and weighing over 1.5 lbs. Contains 3 month supply.

ONLY for cats & kittens over 8 weeks of age and over 1.5 lbs

Apply one tube (0.67 mL) (0.023 fl oz) once a month (30 days).

Three 0.017 fl. oz. (0.50 mL) Applicators in each box. Net Contents: 0.051 fl. oz.


How to Open

  1. Remove product tubes from the package.
  2. Separate one tube from the others. Hold the tube with notched end pointing up and away from the face and body. Use scissors to cut off the narrow end at the notches along the line.

How to Apply

  1. Invert tube over cat and use open end to part cat’s hair.
  2. Squeeze tube firmly to apply all of the solution to the cat’s skin as a spot on the cat’s back between the shoulder blades.

Q. Does ZoGuard Plus expire?

  • No, as long as you store ZoGuard Plus at room temperature and sealed in its original packaging it will not expire.

Q. How old should my dog or cat be before I use ZoGuard Plus?

  • ZoGuard Plus can be used on puppies and kittens 8 weeks or older.

Q. Does my dog or cat have to already be bitten by a flea or tick for ZoGuard Plus to work?

  • No. ZoGuard Plus kills fleas and ticks through contact with your pet’s coat.

Q. Can ZoGuard Plus be used on other pets?

  • No. ZoGuard Plus is only meant for treatment of dogs and cats.

Q. Can I use ZoGuard Plus for Dogs on cats or ZoGuard Plus for Cats on dogs?

  • ZoGuard Plus for Dogs should only be used on dogs. ZoGuard Plus for Cats should only be used on cats.

Q. How do I apply ZoGuard Plus?

  • Remove the product tubes from the package and separate one tube from the others. Hold the vial with the notched tip up and away from the face. Use scissors to snip off the tip at the notches. Invert the vial and use the open tip of the tube to part your dog’s hair between the shoulder blades. Next, squeeze the tube to apply all of the product to your dog’s skin in a single spot between the shoulder blades.

Q:  Where do I apply ZoGuard Plus?

  • Apply all of the product to your dog’s skin in a single spot between the shoulder blades.

Q. How often should I apply ZoGuard Plus?

  • ZoGuard Plus should be applied monthly, or every 30 days. Do not reapply before the month is through. ZoGuard Plus works for a full 30 days.

Q. Will ZoGuard Plus work better if I apply it more often?

  • No. Do not reapply ZoGuard Plus before the month is through. It keeps working for a full 30 days.

Q. When does ZoGuard Plus start working?

  • ZoGuard Plus starts working as soon as it is applied.

Q. When can I bathe my dog after application?

  • Keep your dog from getting wet for 24 hours after application. ZoGuard Plus keeps working for 30 days, even if your dog is bathed or goes swimming. Be sure your dog is completely dry if you apply after a bath.

Q. How soon after application will ZoGuard Plus begin to kill fleas?

  • ZoGuard Plus will kill 100% of the fleas within 4-12 hours after application.

Q. Now that I applied ZoGuard Plus, I am seeing even more fleas. Why?

  • As fleas die they will rise to the top of your dog’s coat. So it is normal to start seeing more fleas after treatment has been applied.

Q. I have treated my dog or cat with ZoGuard Plus but I still see fleas. Why?

  • If ZoGuard Plus was applied before the flea eggs have hatched, you may notice fleas on your pet again.  Consecutive monthly applications of ZoGuard Plus will work to eliminate those fleas. According to the Companion Animal Parasite Council (CAPC) year round usage of a flea and tick control product like ZoGuard Plus is recommended. 

Q. How does ZoGuard Plus work?

  • ZoGuard Plus combines fipronil, the top-selling flea and tick control product, with (S)-methoprene, an insect growth regulator that keeps flea larvae from developing into adults. ZoGuard Plus contains the same flea- and tick-fighting protection as FRONTLINE Plus.

Q. What other insects does ZoGuard Plus kill?

  • ZoGuard Plus also kills chewing lice.

Q What makes ZoGuard Plus different?

  • ZoGuard Plus is one of the only products available, besides FRONTLINE Plus, with the combination of fipronil and (S)-methoprene, making it an effective option for affordable flea and tick control.

Q.Where is ZoGuard Plus made?

  • ZoGuard Plus is manufactured and packaged in the United States. It is approved for use by the U.S. Environmental Protection Agency.

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  • 4 of 5 people found this review helpful:

    1 of 5 stars  Dissappointed
    By Karen in Galena, Missouri on 07/18/2017

    Against my better judgement I took your advice and purchased the flea treatment for my cats, however the frontline formula has not been working in my area for years. I had to wait 30 days and purchase another brand with a different formula. It seems to be working fine.

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05/07/2015 Ellen from Locust Grove Ga

QWhy do cats have to be kept away from others when ZoGuard Plus is applied?
Been using frontline plus and Revolution and neither recommends isolating cats for any length of time after application.

APets should be isolated after application so that the product is not spread from one pet to another, potentially harming another pet that is either another species or already being treated with this or another product and, therefore, at risk of being exposed to too much of the product. It is a precaution for both the pets being treated and other pets with which they may come into contact.

11 of 11 people found this answer helpful.
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12/28/2016 Sarah from Lakewood

QHow long does it take for fleas and chewing lice to be killed after applying ZoGuard Plus for Cats? Does this product kill all life stages of these pests?


ZoGuard Plus will kill fleas within 4-12 hours of application when applied according to the product label. If there are eggs that have not yet hatched, then they would not be exposed to the active ingredients until hatching. Therefore, you may still see some flea activity on treated animals after the initial application. This is one of the main reasons that it is recommend to apply systemic flea treatments every 30 days as directed.†Keep in mind that ZoGuard Plus will not prevent pets from potentially picking up new fleas from the environment, so we always recommend treating indoor and outdoor areas where pets spend time for the most effective flea control. Please take a few moments to review our Flea Treatment Guide for more tips and information.

2 of 2 people found this answer helpful.
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05/26/2017 Val

QIs ZoGuard Plus For Cats safe?
Has this product been tested for safety? I don't see any info about that.


ZoGuard Plus For Cats is safe if used as directed. It has been through manufacturer testing on safety.

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